Dynamics of growth in batch and continuous cultures of Saccharomyces cerevisiae during shifts from aerobiosis to anaerobiosis and reverse

authored by

G. Auling, K. H. Bellgardt, H. Diekmann, M. Thoma

Abstract

Saccharomycescerevisiae H 1022 was cultivated in batch and continuous culture on a glucose substrate. The yeast was subjected to a sudden change from aerobic to anaerobic growth conditions by switching the inlet-gas stream from air to dinitrogen. The dynamics of growth and product formation during the periods of adaptation were studied. A structured growth model based on Monod-Blackman-kinetics was applied to simulate these shift-experiments. The immediate switch of the yeast to maximum anaerobic growth and ethanol production predicted by this model was confirmed very well in the chemostat-experiments. However, a slow adaptation was evident for the switch from anaerobiosis back to aerobiosis.

Organisation(s)

Institute of Automatic Control

Type

Article

Journal

Applied Microbiology and Biotechnology

Volume

19

Pages

353-357

No. of pages

5

ISSN

0175-7598

Publication date

05.1984

Publication status

Published

Peer reviewed

Yes

ASJC Scopus subject areas

Biotechnology, Applied Microbiology and Biotechnology

Electronic version(s)

https://doi.org/10.1007/BF00253784 (Access: Closed)